MULTIGENERATIONAL EFFECTS OF BISPHENOL A OR ETHINYL ESTRADIOL EXPOSURE ON F2 CALIFORNIA MICE (PEROMYSCUS CALIFORNICUS) PUP VOCALIZATIONS.

Multigenerational effects of bisphenol A or ethinyl estradiol exposure on F2 California mice (Peromyscus californicus) pup vocalizations.

Rodent pups use vocalizations to communicate with one or both parents in biparental species, such as California mice (Peromyscus californicus).Previous studies have shown California mice developmentally exposed to endocrine disrupting chemicals, bisphenol A (BPA) or ethinyl estradiol (EE), demonstrate later compromised parental behaviors.Reductions

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Lifestyle and Circadian Health: Where the Challenges Lie?

Modern life is facilitated by extended light hours at night and longer hours of eating.Compromised sleep, sedentary life, and modern diet adversely affect human health.Studies emphasizing importance of evidence-driven longitudinal studies on daily rhythms of human eating and sleeping behaviour provide a baseline for adequate insight into causal fac

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Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers

Background: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy.Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to heterogeneity.Methods: We demonstrate how to quantify

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